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Job Title: Post-Doctoral Training Fellow – Division of Structural Biology
Closing Date of vacancy: 8 February 2012
Division: Structural Biology
Type of Contract: Fixed Term
Length of Contract: 3 years
Salary Range: £27,536 to £33,852 p.a. inclusive Work
Location: London Hours per week: 35

We seek to appoint a Post-Doctoral Training Fellow to the Division of Structural Biology in the new team led by Dr Alessandro Vannini to undertake crystallographic, single particle electron microscopy analysis and biochemical analysis of the RNA Polymerase III transcription apparatus in order to elucidate its role in cancer and other fundamental cellular processes.

The Division of Structural Biology has managed facilities for protein crystallography (Bruker Microstar and CCD detector and crystallisation robots), cryo-electron microscopy (FEI Tecnai F20 and T12), and protein production with expertise in multi-subunit expression (insect cell, yeast and bacterial expression including a 60 L fermentor). The Division is also well equipped with equipment for biophysical analysis (e.g. ITC, fluorescence, multi-angle light scattering).

Applicants should possess a PhD (or equivalent) in biochemistry or molecular biology with a sound knowledge of protein purification for structural biology analysis. Experience in recombinant protein production and purification as well as protein crystallography and/or single particle electron microscopy is essential. Experience in the biochemistry of multi-subunit protein complexes, yeast genetics or protein production in insect cells (MultiBac) would be an advantage.

Appointment will be on Fixed Term Contract for 3 years in the first instance, with a starting salary in the range of £27,536 to £33,852 p.a. inclusive (based on previous post-doctoral experience).

To apply click here:
https://atsv7.wcn.co.uk/saf/login.cgi?owner=5050130&ownertype=fair&jcode=1228522&external=86483

Job Reference No. 1228522