海外

Postdoctoral Fellow-Cell Signaling, Metabolic and Stress Responses and Diabetes-Boston University School of Medicine : Boston, MA, USA
Employer: Boston University - Department of Medicine
Website: http://www.bumc.bu.edu/csdl/
Location: Boston, MA, USA
Type: Postdoctoral
Posted: October 29, 2011
Expires: November 30, 2011

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job description

Postdoctoral position is available at the Boston University School of Medicine. Our research interests focus on the molecular mechanism of novel signaling molecules and nuclear receptors that control energy homeostasis, diabetes. Current research program is to explore the role of AMP-activated protein kinase, NAD-dependent deacetylase Sirtuin (SIRT1), in the control of energy expenditure, diabetes and cardiovascular disease (Cell Metabolism, 2011, FASEB J, 2011, J Biol Chem. 2008, and Diabetes. 2006). The nutrient signaling network has important implications for the understanding of metabolic regulation and its impact of treatment of human metabolic syndromes, such as diabetes and obesity.

Requirements include a Ph.D. in Molecular or Cell Biology, Biomedical Science or similar. We are seeking highly motivated, enthusiastic, and interactive individuals interested in dissecting the molecular mechanisms of metabolic regulation and pathogenesis of insulin resistance, type 2 diabetes and cardiovascular complications in animal models. Previous experience in the generation of transgenic and/or knockout mouse lines is desirable. Strong experience with the signal transduction, molecular and cell biology (e.g. adenoviral transduction of expression or shRNA constructs) are also desirable. Excellent communication and team skills are required.

Please send a cover letter which describes past research experience and a brief statement for research interests and research plan, CV, and contact information of three references to mwzang1@bu.edu.

Mengwei Zang, M.D., Ph.D.,
Associate Professor of Medicine
Boston University School of Medicine
650 Albany Street, Boston, MA 02118